40:51 FDA Status, Safety & Duration 43:30 Stacking Protocols & Best Uses 46:52 Upcoming Genoshack Podcast & Outro We cover: Switching From Tirzepatide to Retatrutide: Why at low doses you can swap directly and why more frequent dosing beats once a week Tesofensine for Anxiety & GLP Transition: Why it's the best next step coming off GLPs and what to watch for if anxiety is already a factor Mitochondrial Stack Order: Why SS-31 comes before MOTS-C every time, what FOXO4 does, and why lifestyle fundamentals come before any peptide HGH Debate Worthless or Essential?: Why HGH is a long play, why secretagogues lose effectiveness as the pituitary ages, and why real HGH wins for men over 40 Which HGH Is Actually Best: Why Somatropin, Serostim and Genotropin are all identical and what the different kit sizes actually mean Firefighter Sleep & Cortisol Protocol: Why cortisol takes the top seat over testosterone, the supplement stack that fixed JD's sleep, and why sunlight and grounding still matter Tesamorelin + Retatrutide for Visceral Fat: Dosing both together, why gaining weight but losing inches is actually the goal, and what body recomposition really looks like Perimenopause Protocol Simplified: Why the Klow blend, TA-1, NAD, SS-31 and creatine cover most bases with minimal injections Bone Density & Osteopenia at 59: Why HGH plus resistance training beats calcium advice, and what's emerging in bone-specific peptide research Insulin Resistance, Anxiety & Tirzepatide in a 30-Year-Old: Why blood sugar normalizing feels like hypoglycemia, why switching to Retatrutide helps, and why NAD can worsen anxiety in some people Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results
Those Having Trouble With Side Effects From Higher Doses Some folks stop taking GLP-1 drugs because the side effects make it tough
Typical weekly range: 28 mg once weekly (gradual escalation over 812 weeks)
There are several risks associated with this off-label approach
Portulaca Oleracea Extract (Purslane Extract): one of the best anti-aging ingredients used in the beauty industry for its high levels of antioxidants, omega-3 fatty acids, glutathione, carotenoids, and coenzyme Q10
Simultaneous induction of Ppara and Ppargc1a underscores enhanced mitochondrial oxidative capacity, while restoration of Pex3 and Crls1 points to improved peroxisomal and mitochondrial integrity
